职称:教授
联系电话:--
email:ayfytyh@126.com
研究方向:认知神经心理学、神经免疫、神经调控、脑血管病
- 个人简介
- 科研项目
- 论文专著
- 专利与技术许可
- 荣誉奖励
个人简历:
田仰华,一级主任医师,皖江学者特聘教授,博士生导师,享受国务院津贴。入选国家百千万人才工程、安徽省杰青、安徽省学术和技术带头人等,擅长神经免疫及罕见病诊治。现任中华医学会神经病学分会青年委员兼痴呆与认知障碍学组委员,中国神经内科医师协会青年委员,中国卒中学会青年理事,安徽省卒中学会副会长等职务。主持获得国家自然科学基金4项。以第一/通讯作者发表SCI论文30余篇,包括Nature Genetics, PNAS, Neuropsychopharmacology, Brain Stimulation等杂志,获得安徽省科技进步一等奖一项(排名第2)以及中国神经内科医师协会杰出青年医师奖。
教育经历:
2008.09-2011.06 安徽医科大学 神经病学 医学博士研究生
2005.09-2008.06 安徽医科大学 神经病学 医学硕士研究生
1998.09-2003.06 安徽医科大学 临床医学 医学学士
研究工作经历:
2003.07-2009.09 安徽医科大学第一附属医院神经内科 住院医师
2009.09-2013.11 安徽医科大学第一附属医院神经内科 主治医师
2013.11-2018.12 安徽医科大学第一附属医院神经内科 副主任医师/教研室副主任
2014.11-2019.09 安徽医科大学神经病学 副教授
2017.07-2018.08 西藏山南市人民医院神经内科 副院长/党委委员
2018.11-2021.09 安徽医科大学第一附属医院毕业后教育处 处长
2018.12-至今 安徽医科大学第一附属医院神经内科 主任医师
2019.09-至今 安徽医科大学第一附属医院神经内科 教授
2021.10-至今 安徽医科大学第二附属医院 执行院长
1.2020年,抑郁症自杀的神经机制及其rTMS干预研究(32071054),国家自然科学基金面上项目,2021-01至2024-12,57万元,在研。
2.2018年,基于精准靶向神经环路的非药物治疗难治性抑郁症的基础与临床(91732303),国家自然科学基金重大研究计划,2018-01至2019-12,60万,顺利结题。
3.2018年,基于静息脑电及 ERP 方法的不同类型重型精神疾病电休克治疗机制的研究(1808085J23),安徽省自然科学基金杰出青年基金,2018-06至2022-06,40万,在研。
4.2017年,睡眠障碍的遗传学研究(973子课题)(2015CB856400),国家重点基础研究发展计划,2015-03至-2019-08,117.74万元,顺利结题。
5.2017年,基于海马精细分区的难治性抑郁症神经遗传学研究(81671354),国家自然科学基金面上项目,2017-01至2020-12,57万元,顺利结题。
6.2016年,危险因素靶向干预与神经环路再激活(2016YFC1305904),国家重点研发计划“重大慢病非传染性疾病防控研究”重点专项, 2016-09至2020-12,25万元,在研。
7.2015年,电休克治疗对抑郁症记忆巩固的抑制作用及其神经机制研究(81471117),国家自然科学基金面上项目,2015-01至2018-12,70万元,顺利结题。
8.2015年,老年期认知与情绪障碍早期预警技术研究,国家精神心理疾病临床医学研究中心,20万元。
9.2012年,基于脑功能连接的忽视症神经机制及rTMS干预的研究(81100806),国家自然科学基金青年基金,2012-01至2014-12,45万元,顺利结题。
2023年:
1. Shugang Cao, Jing Du, Sidi Pan, Juanjuan Zhang, Si Xu, Ling Wei, Yanghua Tian* (last-corresponding author). Case Report: Ofatumumab treatment in a patient with rituximab-intolerant refractory autoimmune GFAP astrocytopathy. Front Immunol. 2023 May 8;14:1164181. doi: 10.3389/fimmu.2023.1164181.
2. Yibing Yan, Yue Wu, Guixian Xiao, Lu Wang, Shanshan Zhou, Ling Wei, Yanghua Tian, Xingqi Wu, Panpan Hu, Kai Wang. White Matter Changes as an Independent Predictor of Alzheimer's Disease. J Alzheimers Dis. 2023;93(4):1443-1455. doi: 10.3233/JAD-221037.
3. Siyu Fan,Yue Yu,Yue Wu,Yiao Kai,Hongping Wang,Yue Chen,Meidan Zu,Xiaonan Pang, Yanghua Tian* (last-corresponding author). Altered brain entropy and functional connectivity patterns in generalized anxiety disorder patients. J Affect Disord. 2023 Jul 1;332:168-175. doi:10.1016/j.jad.2023.03.062. Epub 2023 Mar 26. 4
4.Yu Jiang,Ting Zhang,Mengdan Zhang,Xiaohui Xie,Yanghua Tian,Kai Wang,Tongjian Bai. Apathy in melancholic depression and abnormal neural activity within the reward-related circuit. Behav Brain Res. 2023 Apr 27;444:114379. doi:10.1016/j.bbr.2023.114379.
5.Wanqiu Zhu,Ziwen Gao,Hui Li,Ziang Huang,Xiaohu Li,Haibao Wang,Xingqi Wu,Yanghua Tian,Shanshan Zhou,Xiaoshu Li,Yongqiang Yu. Education reduces cognitive dysfunction in Alzheimer's disease by changing regional cerebral perfusion: An in-vivo arterial spin labeling study. Neurol Sci. 2023 Jul;44(7):2349-2361. doi: 10.1007/s10072-023-06696-x.
6. Xiaohui Xie,Panpan Hu,Yanghua Tian,Bensheng Qiu,Kai Wang,Tongjian Bai. Abnormal resting-state function within language network and its improvement among post-stroke aphasia. Behav Brain Res. 2023 Apr 12;443:114344. doi: 10.1016/j.bbr.2023.114344.
7. Feng Geng,Song Wang,Yanghua Tian, Feng Jiang,Rachel Conrad,Tingfang Liu,Yuanli Liu,Daming Mo,Huanzhong Liu, Yi-Lang Tang. Factors Associated With Utilization of Electroconvulsive Therapy During Psychiatric Hospitalization Among Children and Adolescents in China. J ECT. 2023 Jan 17. doi: 10.1097/YCT.0000000000000898.
8. Chenyu Sun,Vicky Yau,John Patrick Nanola Uy,Scott Lowe, Yanghua Tian* (co-corresponding author). Does viral inoculum play a role in disease severity in COVID-19? J Med Virol. 2023 Feb;95(2):e28532. doi: 10.1002/jmv.28532.
9. Guanglu Li, Jiajia Zhu, Xingqi Wu, Tingting Liu, Panpan Hu, Yanghua Tian* (co-corresponding author), Kai Wang. Baseline free water within the visual processing system predicts future psychosis in Parkinson disease. Eur J Neurol. 2023 Apr;30(4):892-901. doi: 10.1111/ene.15668.
10. Gong-Jun Ji, Jiao Li, Wei Liao, Yingru Wang, Lei Zhang, Tongjian Bai,Ting Zhang,Wen Xie,Kongliang He,Chuyan Zhu,Juergen Dukart,Chris Baeken,Yanghua Tian*(co-corresponding author),Kai Wang. Neuroplasticity-Related Genes and Dopamine Receptors Associated with Regional Cortical Thickness Increase Following Electroconvulsive Therapy for Major Depressive Disorder. Mol Neurobiol. 2023 Mar;60(3):1465-1475. doi: 10.1007/s12035-022-03132-7. 36469225.
11. Gong-Jun Ji,Andrew Zalesky,Yingru Wang,Kongliang He,Lu Wang,Rongrong Du,Jinmei Sun,Tongjian Bai,Xingui Chen, Yanghua Tian, Chunyan Zhu,Kai Wang. Linking Personalized Brain Atrophy to Schizophrenia Network and Treatment Response. Schizophr Bull. 2023 Jan 3;49(1):43-52. doi: 10.1093/schbul/sbac162.
2022年:
1. Yumeng Xin, Tongjian Bai, Ting Zhang, Yang Chen, Kai Wang, Shan Yu, Ning Liu, Yanghua Tian* (last-corresponding author). Electroconvulsive therapy modulates critical brain dynamics in major depressive disorder patients. Brain Stimul. 2022;15(1):214-225. doi:10.1016/j.brs.2021.12.008. IF=8.955
2. Alfredo Spagna, Jason Wang, Isabella Elaine Rosario, Li Zhang, Meidan Zu, Kai Wang, Yanghua Tian* (last-corresponding author). Cognitive Considerations in Major Depression: Evaluating the Effects of Pharmacotherapy and ECT on Mood and Executive Control Deficits. Brain Sci. 2022;12(3):350. doi:10.3390/brainsci12030350. IF=3.394
3. Yuanyuan Li, Yue Li, Qiang Wei, Tongjian Bai, Kai Wang, Jiaojian Wang, Yanghua Tian* (last-corresponding author). Mapping intrinsic functional network topological architecture in major depression disorder after electroconvulsive therapy. J Affect Disord. 2022;311:103-109. doi:10.1016/j.jad.2022.05.067. IF=4.839
4. Jinping Xu, Wenfei Li, Tongjian Bai, Jiaying Li, Jinhuan Zhang, Qingmao Hu, Jiaojian Wang, Yanghua Tian* (last-corresponding author), Kai Wang. Volume of hippocampus-amygdala transition area predicts outcomes of electroconvulsive therapy in major depressive disorder: high accuracy validated in two independent cohorts. Psychol Med. 2022;1-10. doi:10.1017/S0033291722001337. IF=7.723
5. Yajing Pang, Qiang Wei, Shanshan Zhao, Nan Li, Zhihui Li, Fengmei Lu, Jianyue Pang, Rui Zhang, Kai Wang, Congying Chu, Yanghua Tian* (co-corresponding author), Jiaojian Wang. Enhanced default mode network functional connectivity links with electroconvulsive therapy response in major depressive disorder. J Affect Disord. 2022;306:47-54. doi:10.1016/j.jad.2022.03.035. IF=4.839
6. Yue Wu, Yang Ji, Tongjian Bai, Qiang Wei, Meidan Zu, Yuanyuan Guo, Huaming Lv, Aiguo Zhang, Bensheng Qiu, Kai Wang, Yanghua Tian* (last-corresponding author). Nodal degree changes induced by electroconvulsive therapy in major depressive disorder: Evidence in two independent cohorts. J Affect Disord. 2022;307:46-52. doi:10.1016/j.jad.2022.03.045. IF=4.839
7. Ting Zhang, Xiaohui Xie, Qianqian Li, Lei Zhang, Yue Chen, Gong-Jun Ji, Qiangqiang Hou, Tianxia Li, Chunyan Zhu, Yanghua Tian* (co-corresponding author), Kai Wang. Hypogyrification in Generalized Anxiety Disorder and Associated with Insomnia Symptoms. Nature and science of sleep. 2022;14:1009-19. doi:10.2147/nss.S358763 IF=3.384
8. Yuanyuan Li, Xiaohui Yu, Yingzi Ma, Jing Su, Yue Li, Shunli Zhu, Tongjian Bai, Qiang Wei, Benjamin Becker, Zhiyong Ding, Kai Wang, Yanghua Tian* (co-corresponding author), Jiaojian Wang. Neural signatures of default mode network in major depression disorder after electroconvulsive therapy. Cerebral cortex (New York, NY : 1991). 2022. doi:10.1093/cercor/bhac311 IF=4.861
9. Yuanyuan Guo, Xinyi Lv, Juanjuan Zhang, Chenglong Li, Ling Wei, Nong Zhou, Jinping Xu, Yanghua Tian* (co-corresponding author), Kai Wang. Gray matter atrophy and corresponding impairments in connectivity in patients with anti-N-methyl-D-aspartate receptor encephalitis. Brain imaging and behavior. 2022. doi:10.1007/s11682-022-00670-5 IF=3.224
10. Li Zhang, Zhiyong Li, Yu Wu, Yue Yu, Gong-Jun Ji, Yanghua Tian* (co-corresponding author), Kai Wang. Frontothalamic Circuit Abnormalities in Patients With Bipolar Depression and Suicide Attempts. The Journal of clinical psychiatry. 2022;83(6). doi:10.4088/JCP.21m14185 IF=5.906
11. Yu Y, Chen Y, Wu Y, Bai T, Wei Q, Ji Y, Zhang T, Li C, Zhang A, Wang K, Tian Y* (last-corresponding author). The Common Neural Mechanism of Somatic Symptoms of Depression and Anxiety Disorders: A Resting-State Functional Magnetic Resonance Imaging Study. Neuropsychobiology. 2023;82(1):51-60. doi:10.1159/000527276 IF=12.329
12. Jiajia Nie,Qiang Wei,Tongjian Bai,Ting Zhang,Huaming Lv,Li Zhang,Gongjun Ji,Fengqiong Yu,Yanghua Tian* (co-corresponding author), Kai Wang. Electroconvulsive therapy changes temporal dynamics of intrinsic brain activity in depressed patients. Psychiatry Res. 2022;316:114732. doi:10.1016/j.psychres.2022.114732 IF=11.225
13. Zhang L, Li Q, Du Y, Gao Y, Bai T, Ji GJ, Tian Y* (co-corresponding author), Wang K. Effect of high-definition transcranial direct current stimulation on improving depression and modulating functional activity in emotion-related cortical-subcortical regions in bipolar depression. J Affect Disord. 2023;323:570-580. doi:10.1016/j.jad.2022.12.007 IF=6.533
14. Liu Y, Cao S, Du B, Zhang J, Chen C, Hu P, Tian Y, Wang K, Ji GJ, Wei Q. Different Dynamic Nodal Properties Contribute to Cognitive Impairment in Patients with White Matter Hyperintensities. Brain Sci. 2022 Nov 10;12(11):1527. doi: 10.3390/brainsci12111527.
15. Xie X, Hu P, Tian Y, Wang K, Bai T. Transcranial alternating current stimulation enhances speech comprehension in chronic post-stroke aphasia patients: A single-blind sham-controlled study. Brain Stimul. 2022 Nov-Dec;15(6):1538-1540. doi: 10.1016/j.brs.2022.12.001. Epub 2022 Dec 6.
2020年 中国神经内科医师协会“杰出青年医师奖”
2020年 获得国务院特殊津贴
2019年 人社部百千万人才工程“有突出贡献中青年专家”
2019年 安徽省学术技术学术带头人
2018年 安徽省杰出青年科学基金
2017年 安徽医科大学第一附属医院首届杰出青年
2015年 安徽省卫计委青年领军人才
2014年 安徽省学术技术带头人后备人才
2014年 安徽医科大学第一附属医院后备人才
2013年 安徽医科大学国家优青培育对象
2013年 安徽医科大学第二批青年拔尖人才
2013年 安徽医科大学中青年后备人才
科技获奖:
2021年 安徽省科学技术奖二等奖(排名第1)
2019年 安徽省科学技术奖一等奖(排名第2)
2010年 安徽省科学技术奖二等奖(排名第4)